Procurement Summary
Country : United Kingdom
Summary : Biological Services- Models Cryopreservation of Mhra Breeding Stock
Deadline : 21 Feb 2025
Other Information
Notice Type : Tender
TOT Ref.No.: 113820086
Document Ref. No. : CF-2825500D0O000000rwimUAA
Competition : ICB
Financier : Self Financed
Purchaser Ownership : Public
Tender Value : GBP 50000
Purchaser's Detail
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Login to see detailsTender Details
Tenders are invited from establishments who have the capabilities to take on all services related to transgenic colony management.
At the MHRA, the Biological Services facility houses two transgenic mouse breeding colonies. These colonies have been specifically bred to support the Poliomyelitis test work implemented by the Science, Research & Innovation Group.
In-bred transgenic mice with the Human Polio receptor gene provides a practical alternative to the use of non-human primates. These lines are used to assess the neurovirulence of polioviruses and immunogenicity/ protection of vaccines and hence play a key role in the global polio activities of the Agency. Both colonies require refresh, as genetic drift has been observed due to multiple unexpected phenotypic changes. We are therefore seeking assistance in the maintenance and refresh of colonies, possibly looking to utilise already frozen stocks of embryos/ sperm.
Location Of Contract : EN6 3QG
Industry : Laboratory, optical and precision equipments (excl. glasses) - 38000000 Laboratory services - 71900000
Value Of Contract : £50, 000
Published Date : 27 January 2025
Closing Date : 21 February 2025
Documents
Tender Notice