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DEPT OF DEFENSE has floated a tender for Broad-Spectrum Antagonists for Editors (B-Safe). The project location is USA and the tender is closing on 12 Aug 2024. The tender notice number is HR001124S0032, while the TOT Ref Number is 102737420. Bidders can have further information about the Tender and can request the complete Tender document by Registering on the site.
Procurement Summary
Country : USA
Summary : Broad-Spectrum Antagonists for Editors (B-Safe)
Deadline : 12 Aug 2024
Other Information
Notice Type : Tender
TOT Ref.No.: 102737420
Document Ref. No. : HR001124S0032
Financier : Self Financed
Purchaser Ownership : Public
Tender Value : Refer Document
Purchaser's Detail
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Login to see detailsTender Details
Description
The Defense Advanced Research Projects Agency (DARPA) is soliciting innovative proposals to identify and optimize novel molecules that exhibit inhibitory effects on Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-CRISPR associated proteins (CRISPR-Cas) gene editing processes. The Broad-Spectrum Antagonists for Editors (B-SAFE) program is explicitly seeking transformative approaches enabling the discovery or design of novel inhibitors of gene editing technologies with enhanced activity, utility, and breadth of coverage. Novel inhibitor activity will be assessed in vitro over the course of the program and a subset of top performing molecules will be selected for scale-up at quantities sufficient for testing and evaluation by Department of Defense (DoD) stakeholders. In concert, DARPA is interested in exploring methods to rapidly discover inhibitor molecules for novel gene editing technologies beyond CRISPR-Cas systems to keep pace with the rapidly advancing field and promote the safe, controlled use of these technologies. Research that generates incremental improvements to the existing state-of-the-art are specifically excluded.
Active Contract Opportunity Notice ID HR001124S0032 Related Notice Department/Ind. Agency DEPT OF DEFENSE Sub-tier DEFENSE ADVANCED RESEARCH PROJECTS AGENCY (DARPA) Office DEF ADVANCED RESEARCH PROJECTS AGCY
General Information
Contract Opportunity Type: Presolicitation (Original)
All Dates/Times are: (UTC-04:00) EASTERN STANDARD TIME, NEW YORK, USA
Original Published Date: Jun 14, 2024 03:11 pm EDT
Original Response Date: Aug 12, 2024 04:00 pm EDT
Inactive Policy: Manual
Original Inactive Date: Sep 11, 2024
Initiative: None
Classification
Original Set Aside:
Product Service Code: AC11 - NATIONAL DEFENSE R&D SERVICES; DEPARTMENT OF DEFENSE - MILITARY; BASIC RESEARCH
NAICS Code: 541714 - Research and Development in Biotechnology (except Nanobiotechnology)
Place of Performance:
Documents
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