Dna Services: Antibody Gene Synthesis, Subcloning and Plasmid Preparation Tender

Procurement Summary

Country : USA

Summary : Dna Services: Antibody Gene Synthesis, Subcloning and Plasmid Preparation

Deadline : 09 Aug 2024

Other Information

Notice Type : Tender

TOT Ref.No.: 105064403

Document Ref. No. : NOI-NIAID-24-2228446

Competition : ICB

Financier : Self Financed

Purchaser Ownership : Public

Tender Value : Refer Document

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Tender Details

Description

This is a Notice of Intent, not a request for proposal. The National Institute of Allergy and Infectious Diseases (NIAID) of the National Institutes of Health (NIH) intends to negotiate on an other than full and open competition basis with Gene Universal, 200 Continental Dr. Ste 401, Newark, DE19713.

The mission of the NIH Vaccine Research Center (VRC) is to facilitate the development of vaccines against HIV-AIDS. Our goal is to develop immunogens that will elicit broadly neutralizing antibodies and will be used in vaccine design. One of the aims of the project is to obtain atomic level structures of the envelope glycoproteins that are the sole exterior target for neutralizing antibodies. Another aim is to develop neutralizing antibodies against HIV.

Vaccine immunogens are custom designed at VRC and thus is not commercially available. The DNA plasmids for the designed vaccine immunogens and antibodies will be synthesized by a service provider in order to be expressed and purified at VRC for further characterization.

This is a follow-on requirement for the VRC, Vaccine Research Center. Study title is, Generative AI-guided design of HIV-1 cocktail immunogens; study # NAI24007001. Changing provider now will compromise the integrity of our data. We have been using Gene Universal for DNA synthesis services for this ongoing project, and it has proven to support our protocols in the development of vaccines for HIV and other viruses.

No substitutions will be acceptable for these services for this follow-on project NAI24007001

The statutory authority for this sole source requirement is 41 U.S.C.1901 (e) (2) as implemented by FAR 13.106-1 only one responsible source and no other supply of service will satisfy agency requirements. THIS IS NOT A REQUEST FOR PROPOSAL.

All responsible sources that could provide comparable services may submit a capability statement that will be considered by email (subject line shall be referenced, NOI-NIAI...
Active Contract Opportunity Notice ID NOI-NIAID-24-2228446 Related Notice Department/Ind. Agency HEALTH AND HUMAN SERVICES, DEPARTMENT OF Sub-tier NATIONAL INSTITUTES OF HEALTH Office NATIONAL INSTITUTES OF HEALTH NIAID
General Information
Contract Opportunity Type: Combined Synopsis/Solicitation (Original)
All Dates/Times are: (UTC-04:00) EASTERN STANDARD TIME, NEW YORK, USA
Original Published Date: Jul 31, 2024 04:48 pm EDT
Original Date Offers Due: Aug 09, 2024 04:00 pm EDT
Inactive Policy: 15 days after date offers due
Original Inactive Date: Aug 24, 2024
Initiative: None

Classification
Original Set Aside:
Product Service Code: Q301 - REFERENCE LABORATORY TESTING
NAICS Code: 541990 - All Other Professional, Scientific, and Technical Services

Place of Performance: Bethesda, MD 20814 USA

Documents

 Tender Notice