PFAS Hazard Assessments Peer Review Services Tender, USA - 107338264

Procurement Summary

Country : USA

Summary : PFAS Hazard Assessments Peer Review Services

Deadline : 27 Sep 2024

Other Information

Notice Type : Tender

TOT Ref.No.: 107338264

Document Ref. No. : 36C24524Q0913

Competition : ICB

Financier : Self Financed

Purchaser Ownership : Public

Tender Value : Refer Document

Purchaser's Detail

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Tender Details

Description

Seeking Sources:Veterans Health Administration, Network Contracting Office 5, is issuing this request for information/sources sought notice in order to identify companies that have the resources and capabilities to evaluate the toxicology of PFAS compounds, including experience in developing toxicity-based benchmarks, risk assessment, and the creation and refinement of physiologically-based toxicokinetic models.Description of Work: Contractor will conduct an extensive review of various data streams, including toxicological, epidemiological, and environmental information. This review will be integral to developing robust serum concentration models for PFAS compounds, delineating their relationship to potential adverse health effects in the veteran population. Contractor's responsibilities encompass expert peer review of hazard assessments, identification and refinement of serum/blood points of departure (PODs) for each toxic endpoint where sufficient evidence of an adverse effect exists, and the employment of advanced PBPK modeling to predict serum/blood concentrations at these PODs. In scenarios where data is insufficient for PBPK modeling, the contractor is expected to use contemporary, scientifically-defensible extrapolation methods to estimate serum/blood concentrations, aligning these findings with available human evidence from hazard assessments.Technical Qualifications:Contractor must have a documented track record in evaluating the toxicology of PFAS compounds, including experience in developing toxicity-based benchmarks, risk assessment, and the creation and refinement of physiologically-based toxicokinetic models. Key Personnel (i.e., subject matter expert) must have MS or equivalent in Toxicology or related field and at least 10 years of relevant work experience (PhD and 5 years of experience highly desired). Possesses excellent background in area of expertise. Performs tasks that involve digesting and summarizing research papers or analyti...
Active Contract Opportunity
Notice ID : 36C24524Q0913
Related Notice
Department/Ind. Agency : VETERANS AFFAIRS, DEPARTMENT OF
Sub-tier : VETERANS AFFAIRS, DEPARTMENT OF
Office: 245-NETWORK CONTRACT OFFICE 5 (36C245)
General Information
Contract Opportunity Type: Sources Sought (Original)
Original Published Date: Sep 17, 2024 09:34 am EDT
Original Response Date: Sep 27, 2024 11:00 am EDT
Inactive Policy: Manual
Original Inactive Date: Nov 26, 2024
Initiative: None

Classification
Original Set Aside:
Product Service Code: B537 - SPECIAL STUDIES/ANALYSIS- MEDICAL/HEALTH
NAICS Code: 541690 - Other Scientific and Technical Consulting Services

Place of Performance:,

Documents

 Tender Notice

36C24524Q0913.docx